Anti-GAPDH Polyclonal Antibody

品牌：solarbio | 货号：K106389P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K106389P-50ul	solarbio	50ul	960.00元
K106389P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-GAPDH Polyclonal Antibody
别名	GAPD;CDABP0047;OK/SW-cl.12;G3PD;HEL-S-162eP
应用	WB
稀释比例	WB 1:5000.
交叉反应	Human Mouse Rat
蛋白分子量	36kDa
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human GAPDH
性状	液体
Public Immunogen Range	Recombinant protein of human GAPDH
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P04406
克隆类型	Polyclonal Antibody
背景资料	Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimers and Huntingtons disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits.

 
参考文献：

《Neuronostatin promotes soluble Aβ1-42 oligomers –induced spatial learning and memory impairments in mice》 作者:Shaobin Yang,Tingji Shao,Peng Yua,Ruidong Cao,Mingyu Zhang Kang Wen,Maorong Fan Bosheng He 期刊:Behavioural Brain Research 影响因子:2.77 PMID:30753874